I tried a different cable and a different port. I was able to get the ZWO recognized as a USB Super-Speed device rather than as a slave under the USB2 hub. Various programs can usually connect to it but no pictures come through and most of the programs eventually crash (FireCapture, SharpCap, MaximDL, AMCap).
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FireCapture initializes the camera, reports "Capture failed", eventually complains of too many lost frames and then crashes.